Synx Tablet ER should be taken in the dose as advised by your doctor, at the same time each day. It can be taken with or without food to avoid stomach upset. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine. It prevents future harm. If you stop taking it, your chest pain may come back.